Molecular Formula:C31H43N3O49S8.10Na Molecular Weight:1728.08 Purity:≥95% Grade:Pharmaceutical Grade Appearance:white to beige powder Application:Fondaparinux sodium is an antithrombotic anticoagulant, a Factor Xa inhibitor. Fondaparinux sodium is chemically related to low molecular weight heparins. Its pentasaccharide structure corresponds to the antithrombin III (ATIII) binding site of heparin. Fondaparinux sodium binding at this site potentiates the natural inhibitory effect of ATIII against factor Xa by a factor of approximately 300, which results in inhibition of thrombin generation.
It is used to prevent the occurrence of venous thromboembolism in patients undergoing major orthopaedic operations such as hip fracture, major knee surgery or hip replacement. Storage Conditions:−20°C |