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Guanidine Hydrochloride, CAS No: 50-01-1, white crystal, soluble in water and alcohol, almost insoluble in acetone, benzene and ether.

1.It can be used as medicine, pesticide, dye and other organic synthesis intermediates.

2.Guanidine hydrochloride reacts with ethyl cyanoacetate and cyclizes into 2,4-diamino-6-hydroxypyrimidine, which is used to synthesize folic acid. It can also be used as antistatic agent for synthetic fiber.

3.It can also be used as protein denaturant.

4.As a strong denaturant in the experiment of total RNA extraction. Guanidine hydrochloride solution can dissolve protein, leading to cell structure destruction, nuclear protein secondary structure destruction, dissociation from nucleic acid, in addition, RNA enzyme can be inactivated by guanidine hydrochloride and other reducing agents.